what is Insulin shock therapy?

19th May 2024

Insulin shock therapy or insulin coma therapy was a form of psychiatric treatment in which patients were repeatedly injected with large doses of insulin in order to produce daily comas over several weeks  It was introduced in 1927 by Austrian-American psychiatrist Manfred Sakel and used extensively in the 1940s and 1950s, mainly for schizophrenia, before falling out of favor and being replaced by neuroleptic drugs in the 1960s It was one of a number of physical treatments introduced into psychiatry in the first four decades of the 20th century. These included convulsive therapies (carbimazole/metrazol and electroconvulsive therapy), deep sleep therapy, and psychosurgery. Insulin coma therapy and convulsive therapies are collectively known as the shock therapies

About Origins Insulin shock therapy

In 1927, Sakel, who had recently qualified as a medical doctor in Vienna and was working in a psychiatric clinic in Berlin, began to use low (sub-coma) doses of insulin to treat drug addicts and psychopaths. After one of the patients experienced improved mental clarity after having slipped into an accidental coma, Sakel reasoned the treatment might work for mentally ill patients  Having returned to Vienna, he treated schizophrenic patients with larger doses of insulin in order to produce coma deliberately and sometimes convulsions Joseph Wortis, after seeing Sakel practice it in 1935, introduced it to the US. British psychiatrists from the Board of Control visited Vienna in 1935 and 1936, and by 1938, 31 hospitals in England and Wales had insulin treatment units  In 1936, Sakel moved to New York and promoted the use of insulin coma treatment in US psychiatric hospitals.[3] By the late 1940s, the majority of psychiatric hospitals in the US were using insulin coma treatment.